S. Othman Amen1, S. Tharwat Baban2 (1Rostock DE; 2Nottingham GB)
Background: Globally, Coronary Artery Disease (CAD), and its complications such as Acute Myocardial Infarction are the leading cause of morbidity and mortality. Vitamin D deficiency is a prevalent condition and it is emerging as a new risk factor for coronary artery disease. However, the correlation between Vitamin Deficiency and increasing risk of CVD development remains elusive.
To determine the association between vitamin D deficiency with acute myocardial infarction among Kurdish population in relation to age, gender. Vitamin D deficiency was defined as a serum 25-hydroxyvitamin D concentrations ≤20 ng/mL. The role Vitamin D in development of acute MI could be pivotal.
In a case-control study, a total of 222 patients ( 153 male; 69 female; aged 22-80 years) with AMI and 225 gender and age-matched non-CAD individuals as the control group were enrolled. The serum vitamin D concentrations was measured by enzymatic immunoassay.
High significant level of Vitamin D deficiency was observed in AMI patients (95.9%), compared to that in control group (78.4%). it was observed that 67.6% were severely vitamin D deficient (0 to<10 ng/ml) and 4.1% were insufficient. Furthermore, the prevalence of Vitamin D deficiency was greater in male MI patients than female.
Findings of this study show that Vitamin D deficiency is strongly associated with development of acute myocardial infarction. This concludes that Vitamin D deficiency is an important new emerging risk factor for CAD. This implies that supplementation of Vitamin D may be important in maintaining cardiovascular health.