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Poster
Evaluation of the effect of Heart Failure Reversal Therapy (HFRT) on the Exercise Capacity in patients with Chronic Heart Failure and their association with co-morbidities  

R. Sane (Mumbai IN)


Aims: New treatment modalities are needed to improve the aerobic capacity of patients with chronic heart failure(CHF)considering the increasing disease prevalence.This study was done to evaluate the effect of Heart Failure Reversal Therapy(HFRT)on exercise indices viz.VO2max and metabolic equivalents(METs)Methodology:This retrospective study screened data of 147 patients who had visited Madhavbaug Clinics between July 2018 to December 2018.The mean VO2max and METs on day 30 of HFRT initiation was compared with that at baseline.Regression analysis was used to calculate the odds for increase in VO2max and METs by HFRT,in specific co-morbidity.Results: Of the 64 patients who fit the study criteria,majority were males (n=51) with mean age of 57.89 + 8.14 years.Most common co-morbidity was hypertension(HTN)(n=45)followed by diabetes mellitus(DM)(n=36) and coronary artery disease(CAD)(n=27).Mean Vo2maxand METs increased significantly at day 30 of HFRT initiation compared to the mean values on day1(p<0.05).Odds for elevation in VO2max and METs were maximum in patients with myocardial infarction(VO2max: OR=4.95;CI=0.26-91.5.METs: OR=3.46; CI=0.18-65.54),ischemic heart disease (VO2max: OR=2.85;CI=0.32-24.7.METs: OR=1.67;CI=0.18-15.29)or obesity (VO2max: OR=2.57;CI=0.29-22.4. METs: OR=1.5;CI=0.16-13.78).All odds were statistically insignificant (p>0.05Conclusion: HFRT leads to significant increase in the VO2max and METs in CHF patients, indicating improved aerobic capacity. 

    
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            [titel] => Evaluation of the effect of Heart Failure Reversal Therapy (HFRT) on the Exercise Capacity in patients with Chronic Heart Failure and their association with co-morbidities

 

            [text] => 

Aims: New treatment modalities are needed to improve the aerobic capacity of patients with chronic heart failure(CHF)considering the increasing disease prevalence.This study was done to evaluate the effect of Heart Failure Reversal Therapy(HFRT)on exercise indices viz.VO2max and metabolic equivalents(METs)Methodology:This retrospective study screened data of 147 patients who had visited Madhavbaug Clinics between July 2018 to December 2018.The mean VO2max and METs on day 30 of HFRT initiation was compared with that at baseline.Regression analysis was used to calculate the odds for increase in VO2max and METs by HFRT,in specific co-morbidity.Results: Of the 64 patients who fit the study criteria,majority were males (n=51) with mean age of 57.89 + 8.14 years.Most common co-morbidity was hypertension(HTN)(n=45)followed by diabetes mellitus(DM)(n=36) and coronary artery disease(CAD)(n=27).Mean Vo2maxand METs increased significantly at day 30 of HFRT initiation compared to the mean values on day1(p<0.05).Odds for elevation in VO2max and METs were maximum in patients with myocardial infarction(VO2max: OR=4.95;CI=0.26-91.5.METs: OR=3.46; CI=0.18-65.54),ischemic heart disease (VO2max: OR=2.85;CI=0.32-24.7.METs: OR=1.67;CI=0.18-15.29)or obesity (VO2max: OR=2.57;CI=0.29-22.4. METs: OR=1.5;CI=0.16-13.78).All odds were statistically insignificant (p>0.05Conclusion: HFRT leads to significant increase in the VO2max and METs in CHF patients, indicating improved aerobic capacity. 

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Rohit sane
IN-9168766276 Mumbai
shikhacrc.madhavbaug@gmail.com ) [session] => stdClass Object ( [id] => 1 [name] => Poster [date] => 2019-05-09 [start] => 00:00:00 [end] => 00:00:00 [abbr] => P [updated] => [created] => 0000-00-00 00:00:00 ) [formatted_authors] => R. Sane (Mumbai IN) [detail_url] => https://www.iscp2019.com/abstracts/presentation/5 )